Moreau's lab

I have a long-standing interest in protein and membrane trafficking and its impact on fundamental cellular processes in health and disease. For my PhD obtained at Pasteur Institute of Lille in France, I studied intracellular trafficking of Yersinia sp., the family of important human pathogens. During my post-doctoral studies at the Cambridge Institute for Medical Research, I got interested in dynamics of autophagosome biogenesis and implications of this process on development and treatment of neurodegenerative disorders.

I recently moved to the Institute of Metabolic Science (IMS, Cambridge), for which I obtained a New Blood Fellowship from the MRC for 3 years. My main interest lies in the mechanisms of unconventional cytosolic proteins transport to the cell surface. For years cytosolic proteins were spotted at the outer side of the plasma membrane, and although many studies focus on its function at both cellular and whole organism level, our knowledge on the translocation mechanism in very poor, which represents a major gap in our understanding of protein trafficking